Which One Should You Use In Web Design? 
They both have their own particular advantages and disadvantages. 
For web design (which is the medium under focus in this article) the main advantage of web safe fonts is that they load faster, reducing the amount of time it takes for your site to load.
This isn’t a huge difference, but if you’re looking to cut out every wasted millisecond, they make a difference. 
The downside of web safe fonts, though, is that they’re generic. There’s nothing unique or original about them, they’re literally available to everyone. If you want style or artistry, you’ll have to use another web font. 
Web fonts feature a lot more variety; they’re a pool of fonts that’s constantly being added to and expanded on. 
You can get the best web fonts for your brand specifically designed based on what you’re looking for, or you can license a preexisting one online from a font hub. Their main advantage is, of course, originality. If you want a font that stands out, web safe fonts won’t cut it. 
If you’re having trouble deciding. just think about this: if the font is crucial for your brand, then use a web font, if not, use a system font 
Let’s talk about what are the best web fonts and web safe fonts that are out there: 
Top 5 of The Best Web Safe Fonts:  
  • Arial
  • Calibri 
  • Dejavu Sans 
  • Geneva 
  • Helvetica 
Top 5 of The Best Web Fonts: 
  • Devant Pro 
  • Grafton 
  • BM Plex Sans 
  • Italico 
  • Monolith
  • TT Norms Pro 

Choosing a web font for your website is a big decision, shaping both how visitors use your site and how they perceive your brand and how they see to your company logo design. To be unique and gain authority in your web design, it’s often about finding the best web font, rather than the best web safe font.

Applying the right typeface in the right places impacts which elements get seen first, and when used strategically can increase conversions, time-on-site and many other business goals.